Bacteria-derived topologies of Cu 2 O nanozymes exert a variable antibacterial effect.

The ability of bacteria to facilitate fabrication of nanomaterials has been adapted towards bacterial sensing applications. In this work, we fabricate spherical, cubic and truncated octahedron topologies of Cu 2 O nanoparticles via E. coli -facilitated redox reaction in an electrochemical setup. The Cu 2 O nanoparticles exhibit cytochrome c oxidase-like activity with the spherical topology displaying higher catalytic rate compared to the other geometries. The topology-dependent catalytic behavior of Cu 2 O nanoparticles has not been reported previously. The Cu 2 O nanozymes also display E. coli killing activity in a topology-correlated manner. The E. coli mediated redox reaction in an electrochemical setup is being reported for the first time for synthesis of different topologies of Cu 2 O which also exert a variable antibacterial effect.