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Protective effects of long-term nitrate administration against ovariectomy-induced kidney dysfunction in rats.

Nasibeh YousefzadehSajad JeddiMaryam ZarkeshReza NorouziradKhosrow KashfiAsghar Ghasemi
Published in: Pharmacological reports : PR (2023)
Low-dose long-term nitrate administration protects against ovariectomy-induced kidney dysfunction in rats. This effect is associated with reducing ovariectomy-induced oxidative stress and restoring eNOS-derived NO deficiency in systemic circulation and the kidney.
Keyphrases
  • low dose
  • high glucose
  • diabetic rats
  • bone loss
  • oxidative stress
  • nitric oxide
  • drug induced
  • endothelial cells
  • drinking water
  • high dose
  • signaling pathway
  • nitric oxide synthase
  • pi k akt