Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy.
Pradyumna AgasthiHemalatha NarayanasamyDan SorajjaJames SlackFarouk MookadamPublished in: Case reports in cardiology (2018)
Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.
Keyphrases
- acute myeloid leukemia
- heart failure
- ejection fraction
- drug induced
- liver failure
- respiratory failure
- aortic stenosis
- bone marrow
- aortic dissection
- left ventricular
- case report
- atrial fibrillation
- depressive symptoms
- coronary artery disease
- sleep quality
- oxidative stress
- extracorporeal membrane oxygenation
- intensive care unit
- transcatheter aortic valve replacement
- physical activity
- combination therapy
- smoking cessation
- aortic valve
- acute respiratory distress syndrome