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Molecular risk factors for locoregional recurrence in resected non-small cell lung cancer.

Wei GuoTao ZhangRunze LiXiaoxi ChenJiaohui PangHua BaoXue WuYang ShaoBin QiuShugeng GaoJie He
Published in: Cancer medicine (2023)
Nearly half of disease recurrences after surgery for NSCC involved locoregional sites. We identified genomic biomarkers from baseline tumor and ctDNA samples which showed promising prognostic value for LR only. This can help identify patients who had a higher risk of locoregional recurrence regardless of the risk of distant metastasis.
Keyphrases
  • lymph node
  • free survival
  • copy number
  • gene expression
  • single molecule
  • circulating tumor
  • dna methylation