Steroidal dimer by001 inhibits proliferation and migration of esophageal cancer cells via multiple mechanisms.

Sai-Qi WangKai-Rui ZhouXiao-Li ShiHui-Fang LvLiang-Yu BieWei-Jie ZhaoXiao-Bing Chen

Published in: Cancer chemotherapy and pharmacology (2018)

These findings suggested that by001 may inhibited proliferation of esophageal cancer cells through mitochondria and death receptor-mediated apoptotic pathways, autophagy induction, as well as suppressed migration of esophageal cancer cells.

Keyphrases

cell death
cell cycle arrest
induced apoptosis
signaling pathway
endoplasmic reticulum stress
oxidative stress
anti inflammatory drugs
pi k akt
endoplasmic reticulum