Preparation Of Nanobubbles Modified With A Small-Molecule CXCR4 Antagonist For Targeted Drug Delivery To Tumors And Enhanced Ultrasound Molecular Imaging.

Yanli PengLianhua Zhu Luofu WangYu LiuKejing FangMinmin LanDaijia ShenDeng LiuZhiping YuYanli Guo

Published in: International journal of nanomedicine (2019)

PTX-AMD070 NBs improved the ultrasound imaging effect in CXCR4+ xenograft tumors and facilitated targeted therapy combined with UTND. Therefore, this study provides an effective method for the integration of ultrasound molecular imaging and targeted therapy of malignant tumors.

Keyphrases

small molecule
drug delivery
magnetic resonance imaging
cancer therapy
ultrasound guided
protein protein
computed tomography
molecularly imprinted
mass spectrometry
drug release