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[Gastric cancer with impaired DNA unpaired nucleotide repair system].

D V RianzhinGrigory RaskinM S MukhinaI V RykovS O KusinO V Khodyreva
Published in: Arkhiv patologii (2023)
This article presents a case of successful treatment of inoperable gastric cancer with impaired mismatched nucleotide repair system (dMMR/MSI-H) in a 72-year-old patient. In view of age, somatic status and the presence of comorbidity, it was decided to prescribe anti-PD-1 therapy in the 1st line of treatment. Currently, after a 2-year course of treatment, the patient is in stable remission.
Keyphrases
  • case report
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  • gene expression
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  • copy number
  • replacement therapy