Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients.
Nobuhisa IshiguroNaoko KosekiMiki KaihoTadashi ArigaHideaki KikutaTakehiro TogashiKoji ObaKeisuke MoritaNaoko NaganoMasanori NakanishiKazuya HaraKyosuke HazamaToru WatanabeTatsuru YamanakaSatoshi SasakiHideto FuruyamaMutsuo ShibataSatoru ShidaAkihito IshizakaYuichi TabataHayato AoyagiHiroyuki NaitoMikio YoshiokaAtsuko HorinoTsuyoshi Kenrinull nullPublished in: PloS one (2017)
Both minocycline and tosufloxacin showed good in vitro activities against MRMP. Minocycline, but not tosufloxacin, shortened the duration of fever in pediatric patients infected with MRMP compared to the duration of fever in patients treated with macrolides.