Prospective evaluation of XRCC-1 Arg194Trp polymorphism as bio-predictor for clinical outcome in locally advanced laryngeal cancer undergoing cisplatin-based chemoradiation.

Vijay Parshuram RaturiHidehiro HojoM L B BhattMohammad SuhelChen-Ta WuYanping BeiMasaki NakamuraMasayuki OkumuraHaiqin ZhangDevendra ParmarAvinash BadajenaRahul SinghSaurabh KumarTridev KatiyarJalaj Gaur

Published in: Head & neck (2020)

XRCC-1 polymorphic variants have significantly higher grade of >2 ARIT and may have improved trend for treatment response and PFS.

Keyphrases

locally advanced
rectal cancer
dna repair
neoadjuvant chemotherapy
squamous cell carcinoma
papillary thyroid
radiation therapy
phase ii study
squamous cell
copy number
dna damage
lymph node metastasis
oxidative stress
childhood cancer
young adults