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Optimized peripheral blood progenitor cell mobilization for autologous hematopoietic cell transplantation in children with high-risk and refractory malignancies.

Eliska FurlongJesper JensenMark WoodardKatherine GriffithsGeoff KnightMarian SturmFiona KerrHazel GoughNatasha BearTina L CarterCatherine H ColeRishi S KotechaShanti Ramachandran
Published in: Pediatric transplantation (2019)
Our approach to HPC mobilization by means of chemotherapy and single myeloid growth factor combined with optimal collection timing facilitated by continuous apheresis flow resulted in highly effective HPC harvest in children and adolescents with high-risk cancers.
Keyphrases
  • growth factor
  • peripheral blood
  • bone marrow
  • young adults
  • dendritic cells
  • acute myeloid leukemia
  • cell therapy
  • locally advanced
  • squamous cell carcinoma
  • stem cells