Extent of piriform cortex resection in children with temporal lobe epilepsy.
Rory J PiperDebayan DasguptaMaria H ErikssonMathilde RipartAlmira MoosaAswin ChariKiran K SeunarineChris A ClarkJohn Sidney DuncanDavid W CarmichaelMartin M TisdallTorsten BaldewegPublished in: Annals of clinical and translational neurology (2023)
This is the first study demonstrating that, in children with TLE and hippocampal atrophy, more extensive temporal PC resection is associated with a greater chance of seizure freedom-compatible with an adult series in which 85% of patients had hippocampal sclerosis. In a combined group of children with and without hippocampal atrophy, the extent of PC resection was not associated with seizure outcome, suggesting different epileptogenic networks within this cohort.