5-Methylthiopentyl Isothiocyanate, a Sulforaphane Analogue, Inhibits Pro-inflammatory Cytokines by Regulating LPS/ATP-mediated NLRP3 Inflammasome Activation.

Su-Bin ChoiJi-Hye KimSehee KwonNa-Hyun AhnJoo-Hee LeeWoong-Suk YangCheorl-Ho KimSeung-Hoon Yang

Published in: Current pharmaceutical biotechnology (2023)

These results indicated the anti-inflammatory effects of 5-methylthiopentyl isothiocyanate (berteroin) by regulating NLRP3 inflammasome activation, suggesting that berteroin could be the potential natural drug candidate for the regulation of inflammation.

Keyphrases

nlrp inflammasome
anti inflammatory
oxidative stress
inflammatory response
risk assessment
climate change
drug induced
electronic health record