Mass Cytometry Reveals Classical Monocytes, NK Cells, and ICOS+ CD4+ T Cells Associated with Pembrolizumab Efficacy in Patients with Lung Cancer.

Philippe Rochigneux Aaron E Lisberg Alejandro Garcia Samuel Granjeaud Anne Madroszyk Stéphane Fattori Anthony Goncalves Raynier Devillier Pauline Maby Nassim Salem Laurent Gorvel Brice Chanez Jaklin Gukasyan James Carroll Jonathan Wade Goldman Anne-Sophie Chretien Daniel Olive Edward B Garon

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

As this immune monitoring is easy in routine practice, we anticipate our findings may improve prediction of ICI benefit in patients with advanced NSCLC.

Keyphrases

nk cells
advanced non small cell lung cancer
small cell lung cancer
primary care
healthcare
single cell
clinical practice
epidermal growth factor receptor
dendritic cells
peripheral blood
quality improvement