Risk of colorectal cancer in patients with primary sclerosing cholangitis and concomitant inflammatory bowel disease compared with primary sclerosing cholangitis only.

Taranika Sarkar DasKimberly HoJahnavi UdaikumarBryan ChenOlivia DelauAasma ShaukatIra JacobsonRaiya Sarwar

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)

Our study revealed a significantly heightened CRC risk in PSC-IBD patients compared with those with PSC-only. Importantly, individuals with PSC-only also face a greater CRC risk compared with the general population. Individuals with PSC-alone may require extended screening and surveillance colonoscopy intervals compared with those with PSC-IBD, yet still require more frequent monitoring than screening guidelines recommend for the general population.

Keyphrases

ulcerative colitis
end stage renal disease
ejection fraction
newly diagnosed
public health
prognostic factors
single cell
clinical practice
patient reported outcomes
patient reported