Regulation of TRPV1 channel in monosodium urate-induced gouty arthritis in mice.

Xiuqi XuZiqi YuanShijia ZhangGuang LiGuangqin Zhang

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2022)

These findings identified an important role of TRPV1 in mediating mechanical hyperalgesia in MSU-induced gouty arthritis and further suggest that TRPV1 can be regarded as a potential new target for the clinical treatment of gouty arthritis.

Keyphrases

rheumatoid arthritis
neuropathic pain
high glucose
diabetic rats
drug induced
oxidative stress
endothelial cells
skeletal muscle