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Germline testing of BRCA1 , BRCA2 , PALB2 and CHEK2 c.1100delC in 1514 triple negative familial and isolated breast cancers from a single centre, with extended testing of ATM , RAD51C and RAD51D in over 400.

Emma Roisin WoodwardFiona LallooClaire FordeSarah PughGeorge Joseph BurghelHelene SchlechtElaine F HarknessAnthony HowellSacha J HowellAshu GandhiD Gareth Evans
Published in: Journal of medical genetics (2024)
PGVs.
Keyphrases
  • dna repair
  • dna damage
  • dna damage response
  • breast cancer risk
  • oxidative stress
  • childhood cancer