Fibroblast-like synovial cell production of extra domain A fibronectin associates with inflammation in osteoarthritis.
Tue Wenzel KragstrupDong H SohnChristin M LepusKazuhiro OnumaQian WangWilliam H RobinsonJeremy SokolovePublished in: BMC rheumatology (2019)
The disease process in OA shares features with the chronic wound healing response. Our findings support utilizing ED-A fibronectin for drug delivery or therapeutic targeting to reduce pro-inflammatory responses in OA.