Automated Image Analysis of Keratin 7 Staining Can Predict Disease Outcome in Primary Sclerosing Cholangitis.

Sjöblom NelliBoyd SonjaManninen AnniinaBlom SamiKnuuttila AnnaFärkkilä MarttiArola Johanna

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2022)

The K7-staining of histological liver specimens in PSC provides significant information on disease outcomes through objective and reproducible data, including variables that cannot be measured by a human pathologist. The K7-AI model 2.0 could serve as a prognostic tool for clinical endpoints and as a surrogate marker in drug trials. This article is protected by copyright. All rights reserved.

Keyphrases

endothelial cells
machine learning
artificial intelligence
deep learning
high throughput
big data
metabolic syndrome
weight loss
ulcerative colitis