A specific tRNA half, 5'tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2.
En-Wei TaoHao-Lian WangWing Yin ChengQian-Qian LiuYing-Xuan ChenQin-Yan GaoPublished in: Journal of experimental & clinical cancer research : CR (2021)
In summary, the findings revealed a specific 5'tiRNA-His-GTG-engaged pathway in CRC progression and provided clues to design a novel therapeutic target in CRC.
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