SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma.

Young-Im KimYu-Chou TsengGamze AyazShasha WangHualong YanWendy du BoisHoward YangTao ZhenMaxwell P LeePaul LiuRosandra N KaplanJing Huang

Published in: Cell & bioscience (2023)

The findings of this study represent a significant advancement in our understanding of the transcriptional network present in OS cells, providing valuable insights that may contribute to the development of targeted therapies for OS.

Keyphrases

transcription factor
induced apoptosis
gene expression
stem cells
endoplasmic reticulum stress