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Effects of Omalizumab Treatment in Patients With Recalcitrant Nasal Polyposis and Mild Asthma: A Multicenter Retrospective Study.

Miguel Armengot-CarcellerMaría José Gómez-GómezCarmen García-NavalónEncarna Doménech-CamposNoelia Muñoz-FernándezAinhoa García-Lliberós de MiguelJaime Marco-AlgarraMarta Palop-CerveraAlfonso García Piñero
Published in: American journal of rhinology & allergy (2020)
Omalizumab was effective for the treatment of patients with recalcitrant CRSwNP and mild asthma, even when AERD was present, by reducing NP size and improving QoL; treatment time was a key factor. SNOT-22 improvements were not explained by decreases in TPS, indicating that omalizumab may be effective in all patients, regardless of polyp size.
Keyphrases
  • chronic obstructive pulmonary disease
  • clinical trial
  • lung function
  • prognostic factors
  • allergic rhinitis