Brain White Matter Microstructure as a Risk Factor for Cognitive Decline After Chemotherapy for Breast Cancer.

Michiel B de RuiterLiesbeth RenemanJacobien M KiefferHester S A Oldenburg Sanne B Schagen

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)

Low FA may reflect low white matter reserve. This may be a risk factor for cognitive decline after chemotherapy for BC. If validated in future trials, identification of patients with low white matter reserve could improve patient care, for example, by facilitating targeted, early interventions or even by influencing choices of patients and doctors for receiving chemotherapy.

Keyphrases

white matter
cognitive decline
mild cognitive impairment
multiple sclerosis
locally advanced
newly diagnosed
ejection fraction
physical activity
rectal cancer
patient reported outcomes
medical students
functional connectivity
breast cancer risk
childhood cancer