CREG Protects Retinal Ganglion Cells loss and Retinal Function Impairment Against ischemia-reperfusion Injury in mice via Akt Signaling Pathway.

Siyu ZengLei DuGuojing LuYiqiao Xing

Published in: Molecular neurobiology (2023)

Our results demonstrated that CREG protected RGCs from RIRI and alleviated retinal apoptosis by activating Akt signaling. In addition, CREG also improved retinal function and visual acuity.

Keyphrases

signaling pathway
induced apoptosis
cell cycle arrest
pi k akt
optical coherence tomography
diabetic retinopathy
optic nerve
epithelial mesenchymal transition
endoplasmic reticulum stress
cell proliferation
cell death
type diabetes
high fat diet induced
insulin resistance
wild type