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A Cryoprotectant-Gel Composite Designed to Preserve Articular Cartilage during Frozen Osteoarticular Autograft Reconstruction for Malignant Bone Tumors: An Animal-Based Study.

Chao-Ming ChenYi-Chun ChenJir-You WangCheng-Fong ChenKuang-Yu ChaoPo-Kuei WuWei-Ming Chen
Published in: Cartilage (2022)
Our study proved that CGC could effectively prevent cartilage surface and chondrocytes from cryoinjury after LN freezing. Freezing articular cartilage surrounded with high concentration of CGC can be a better alternative to preserve articular cartilage during limb salvage surgery for malignant bone tumor.
Keyphrases
  • bone mineral density
  • minimally invasive
  • soft tissue
  • bone loss
  • extracellular matrix
  • bone regeneration
  • postmenopausal women
  • surgical site infection