C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation.

Sara Ortiz-RiveroCristina BaqueroLuis Hernández-CanoJuan José Roldán-EtcheverrySara Gutiérrez-HerreroCristina Fernández-InfanteVíctor Martín-GranadoEduardo AnguitaJosé María de PeredaAlmudena PorrasCarmen Guerrero

Published in: Cell communication and signaling : CCS (2018)

All these data indicate that C3G plays a significant role in different steps of megakaryopoiesis, acting through a mechanism dependent on its GEF activity.

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machine learning
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