Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity.
Gayathri PandeyMichael J SeayJacquelyn L MeyersDavid B ChorlianAshwini Kumar PandeyChella KamarajanMorton EhrenbergDaniel PittiSivan KinreichStacey Subbie-Saenz de ViteriLaura AcionAndrey AnokhinLance O BauerGrace ChanHoward J EdenbergVictor M HesselbrockSamuel KupermanVivia V McCutcheonKathleen K BucholzMarc A SchuckitBernice PorjeszPublished in: Alcoholism, clinical and experimental research (2020)
Density (vs. dichotomous) measures seem to present more robust associations with alcohol outcomes. However, associations of dichotomous and density FH measures with different alcohol outcomes (behavioral vs. neural) varied across gender and race/ethnicity. These findings have great applicability for alcohol research examining FH of AUD.