Risk-reducing mastectomy decisions among women with mutations in high- and moderate- penetrance breast cancer susceptibility genes.
Jacob G ComeauxJulie O CulverJohn E LeeDanielle S DondanvilleHeather L McArthurEmily A QuinnNicholas GormanCharité N RickerMing LiCaryn LermanPublished in: Molecular genetics & genomic medicine (2022)
Although national guidelines do not recommend RRM for moderate penetrance carriers, the rates of RRM for this population approached those for BRCA mutation carriers. Further insights are needed to better support RRM decision-making in this population.