IFN-γ or IL-4 polarization impacts the response of gingival fibroblasts to oral bacteria.

Ju Young JangGeum Hee ChoiSuk Ji

Published in: Journal of periodontal research (2021)

Polarization of GFs with IFN-γ or IL-4 affected the way that GFs responded to oral bacteria through up or downregulation of inflammatory responses and extracellular matrix control.

Keyphrases

extracellular matrix
dendritic cells
immune response
cell proliferation
signaling pathway