Convalescent plasma therapy for the treatment of patients with COVID-19: Assessment of methods available for antibody detection and their correlation with neutralising antibody levels.
Heli HarvalaMatthew L RobbNick WatkinsSamreen IjazSteven DicksMonika PatelPiyada SupasaDejnirattisai WanwisaChang LiuJuthathip MongkolsapayaAbbie BownDaniel BaileyRichard VipondNicholas GraysonNigel TempertonSunetra GuptaRutger J PloegJai BoltonAlex FyfeRobin GopalPeter SimmondsGavin ScreatonCraig ThompsonTim BrooksMaria ZambonGail MiflinDavid J RobertsPublished in: Transfusion medicine (Oxford, England) (2020)
Robust associations between nAb titres and reactivity in several ELISA-based antibody tests demonstrate their possible utility for scaled-up production of convalescent plasma containing potentially therapeutic levels of anti-SARS-CoV-2 nAbs.