The Clinical Course of SARS-CoV-2 Infection in Patients With Autoimmune Neutropenia: A Retrospective Case Series Study.
Gioacchino Andrea RotuloGiulia CeglieAnnalisa CandinoAntonella MerolaElisa ProfetiCarmela GiancottaStefania MercadanteVeronica SantilliNicola CotugnoPaolo PalmaGiuseppe PalumboAndrea FinocchiPublished in: The Pediatric infectious disease journal (2023)
Severe acute respiratory syndrome coronavirus 2 infection in children with autoimmune neutropenia may be a cause for concern. In this retrospective study, none of the 24 autoimmune neutropenia cases manifested severe coronavirus disease 2019. We found a significant improvement in neutrophils and a reduction in lymphocytes at post-infection follow-up compared with the median of previous values. We speculate that this paradoxical effect may be due to postinfection immunological phenomena.