HIV-1 coreceptor tropism: A syllogistic connection with The Veterans Aging Cohort Study Index and the CD4/CD8 ratio.

Armando LeoneNicolò de GennaroClaudia FabrizioLuigia ScudellerLuciana LeporeAntonella LagioiaGrazia PunziAnnalisa SaracinoGioacchino AngaranoLaura Monno
Published in: PloS one (2019)
Our study confirms an association between pre-therapy CRT, CD4/CD8 ratio and VACS. A successful cART regimen positively affects the CD4/CD8 ratio; however, the disadvantage conferred by a non-R5 CRT is maintained overtime. The restoration of VACS in all patients could be directly due to variables included in the VACS calculation and to factors that adversely influence these variables.