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RAMS11 promotes CRC through mTOR-dependent inhibition of autophagy, suppression of apoptosis, and promotion of epithelial-mesenchymal transition.

Md Zahirul Islam KhanHelen Ka Wai Law
Published in: Cancer cell international (2021)
In sum, our results suggested that RAMS11 is an important oncogene in CRC pathogenesis. Targeting RAMS11 could be a potential therapeutic strategy for CRC management.
Keyphrases
  • epithelial mesenchymal transition
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • signaling pathway
  • cell cycle arrest
  • transforming growth factor
  • cell proliferation
  • cancer therapy
  • drug delivery