A Systematic Review of Animal Models of Disuse-Induced Bone Loss.

Mikkel Bo BrentAnnemarie BrüelJesper Skovhus Thomsen

Published in: Calcified tissue international (2021)

Multiple animal models of disuse-induced bone loss exist, and several species of animals have successfully been studied. The complexity of disuse-induced bone loss warrants rigid research study designs. This systematic review emphasized the need for standardization of animal disuse research and reporting.

Keyphrases

bone loss
systematic review
high glucose
diabetic rats
drug induced
endothelial cells
oxidative stress
meta analyses