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Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances.

Wilson NandoloYuri T UtsunomiyaGábor MészárosMaria WurzingerNegar KhayadzadehRafaela B P TorrecilhaHenry A MulindwaTimothy N GondwePatrik WaldmannMaja FerenčakovićJosé F GarciaBenjamin D RosenDerek BickhartCurt P van TassellIno CurikJohann Sölkner
Published in: Genetics, selection, evolution : GSE (2018)
Our findings show that a significant proportion of the ROH islands in the bovine genome are artefacts due to CNV or SNP coverage gaps.
Keyphrases
  • copy number
  • genome wide
  • mitochondrial dna
  • dna methylation
  • gene expression
  • healthcare