Secondary metabolites from an endophytic fungus Trichoderma erinaceum with antimicrobial activity towards Pythium ultimum .

Chemical investigation of the endophytic fungus, Trichoderma erinaceum , isolated from healthy and asymptomatic common bean field crop, resulted in the isolation of a new alkene, ( Z )-5-amino-5-(1,1,2-trihydroxybuta-1,3-dienyloxy)pentane-6,7,8,9-tetraol ( 1 ), together with five known compounds ( 2 - 6 ). The structures of the compounds were elucidated by analysis of their spectroscopic data including 1 D, 2 D NMR, ESI-HRMS and literature data. The organic crude extract and the compound isolated from T. erinaceum significantly (p ≤ 0.05) inhibited the mycelial growth of Pythium ultimum .