Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin.

Xiaotong YangXiaoying MaOcholi DonYuanlin SongXiaoyan ChenJianwen LiuJieming QuYun Feng

Published in: Stem cell research & therapy (2020)

The therapeutic effect of combination MSCs of liraglutide on ALI was higher than that of MSCs alone or liraglutide alone, and liraglutide could alleviate the symptoms of ALI by reducing MSCs apoptosis.

Keyphrases

mesenchymal stem cells
umbilical cord
cell death
bone marrow
cell therapy
cell proliferation
endoplasmic reticulum stress
epithelial mesenchymal transition
stem cells
cell cycle arrest
sleep quality
physical activity
inflammatory response
signaling pathway