Autologous versus allogeneic versus umbilical cord sera for the treatment of severe dry eye disease: a double-blind randomized clinical trial.
Marina Rodríguez Calvo de MoraCayetano Domínguez-RuizFrancisco Barrero-SojoGustavo Rodríguez-MorenoCristina Antúnez RodríguezLaura Ponce VerdugoMaría Del Carmen Hernández LamasLuisa Hernández-GuijarroJacinto Villalvilla CastilloIdefonso Fernández-Baca CasaresIsidro Prat ArrojoDavide BorroniCarmen Alba LineroFrancisco Zamorano-MartinAntonio Moreno-GuerreroCarlos Rocha de LossadaPublished in: Acta ophthalmologica (2021)
The three sera were effective in the treatment of severe DES. CS did not contain a higher proportion of molecules compared to AS/HS. More research is needed to assess the effect of AS in patients with DES and autoimmune diseases.