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Is serum uric acid a predictor of long-term renal outcome in lupus nephritis?

Michelle Remião Ugolini LopesSamara S GavinierElaine LeonVilma Trindade VianaEduardo Ferreira BorbaEloisa Bonfá
Published in: Clinical rheumatology (2019)
• Previous studies reported an association between increased serum uric acid level and short-term renal damage in lupus patients. • The predictive value of serum uric acid for the development of long-term renal dysfunction in lupus nephritis was never assessed. • At 12 months of follow-up serum uric acid clearly differentiated good from poor long-term renal outcome in lupus nephritis. • SUA level < 6.05 mg/dL at 12 months of follow-up was a predictor of good long-term renal outcome in lupus nephritis.
Keyphrases
  • uric acid
  • metabolic syndrome
  • end stage renal disease
  • oxidative stress
  • systemic lupus erythematosus
  • newly diagnosed
  • chronic kidney disease
  • ejection fraction
  • peritoneal dialysis