Proof-of-principle Phase I results of combining nivolumab with brachytherapy and external beam radiation therapy for Grade Group 5 prostate cancer: safety, feasibility, and exploratory analysis.

Zhigang YuanDaniel FernandezJasreman DhillonJulieta Abraham-MirandaShivanshu AwasthiYoungchul KimJingsong ZhangRohit JainAmparo SernaJulio M Pow-SangMichael PochRoger LiBrandon ManleyAngelina FinkArash NaghaviJavier F Torres-RocaG Daniel GrassSungjune KimKujtim LatifiDylan HuntPeter A S JohnstoneKosj Yamoah

Published in: Prostate cancer and prostatic diseases (2020)

Combination of nivolumab with ADT and HDR is well tolerated and associated with evidence of increased immune infiltration and antitumor activity.

Keyphrases

prostate cancer
high dose
radical prostatectomy
radiation therapy
low dose
rectal cancer