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Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients.

Dirk van LierMatthijs KoxKarine SantosHans van der HoevenJanesh PillayPeter Pickkers
Published in: ERJ open research (2021)
Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation https://bit.ly/2MU1z4z.
Keyphrases
  • angiotensin converting enzyme
  • angiotensin ii
  • vascular smooth muscle cells
  • sars cov