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Evaluating immunity to SARS-CoV-2 in nursing home residents using saliva IgG.

Morgan Jane KatzChristopher D HeaneyNora PisanicLeigh SmithBenjamin F BigelowFatima SheikhAlec BoudreauKate KruczynskiYea-Jen HsuAlejandra B SalinasSara E CosgroveClare Rock
Published in: Journal of the American Geriatrics Society (2022)
Positive SARS-COV-2 IgG in saliva was concordant with prior infection (Anti N, S, RBD) and vaccination (Anti S, RBD) and remained above positivity threshold for up to 9 months from infection. Salivary sampling is a non-invasive method of tracking immunity and differentiating between prior infection and vaccination to inform the need for boosters in LTC residents and staff.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • long term care