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Doubtful swelling on clinical examination reflects synovitis in rheumatoid arthritis.

Peter MandlPaul StudenicGabriela SuppMartina DurechovaStefanie HaiderMichaela LehnerTanja StammJosef S SmolenDaniel Aletaha
Published in: Therapeutic advances in musculoskeletal disease (2020)
Clinical doubt in the assessment of joint swelling constitutes an intermediate state between unequivocal swelling and the lack thereof also regarding the objectively quantified level of inflammation. In order to increase sensitivity for joint inflammation, the historical clinical approach of considering doubtful swelling the absence of swelling should be revisited to interpret clinical doubtfulness as an indication of swelling.
Keyphrases
  • rheumatoid arthritis
  • oxidative stress
  • ankylosing spondylitis
  • idiopathic pulmonary fibrosis