Dose-escalated neoadjuvant chemoradiotherapy for locally advanced oesophageal or oesophagogastric junctional adenocarcinoma.
Victor Duque-SantanaFernando López-CamposMargarita MartinLira PelariAntonio HernandezMireia ValeroJulio Galindo ÁlvarezPablo Priego JiménezMarta Cuadrado AyusoFederico LongoMaría Caminoa-LizarraldeSonsoles SanchoPublished in: Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology (2022)
In our study we found a trend towards a higher complete pathological response-rate and disease-free survival in the intensification group compared to the standard group, with no differences in gastrointestinal toxicity. Well-designed randomized and controlled trials are needed to obtain conclusive data.