Association of Uncoupling Protein 1 (UCP1) gene polymorphism with obesity: a case-control study.

Shahanas ChathothMona H IsmailChittibabu VatteCyril CyrusZhara Al AliKhandaker Ahtesham AhmedSadananda AcharyaAisha Mohammed Al BarqiAmein Al Ali

Published in: BMC medical genetics (2018)

The rs1800592 and rs3811791 of UCP1 gene are associated with obesity in general and in the moderate-obese group in particular. The associated UCP1 polymorphisms in the moderate-obese group may regulate the impaired energy metabolism which plays a significant role in the initial stages of obesity.

Keyphrases

weight loss
metabolic syndrome
insulin resistance
type diabetes
bariatric surgery
adipose tissue
high fat diet induced
weight gain
high intensity
obese patients
gene expression
dna methylation
physical activity
nitric oxide