Durability of sustained virological response to glecaprevir/pibrentasvir and resistance development: A long-term follow-up study.
Fred PoordadFranco FelizartaBetty B YaoJ Scott OvercashTarek HassaneinKosh AgarwalEdward J GaneDavid ShawMichael WatersPreethi KrishnanAndrew ToppMargaret BurroughsFrederik NevensPublished in: Liver international : official journal of the International Association for the Study of the Liver (2022)
Glecaprevir/pibrentasvir demonstrated long-term durability of efficacy after SVR12 was achieved. Hepatic-related decompensation events were not seen. Owing to low incidence of virologic failure, conclusions were not drawn on persistence of resistance-associated substitutions.