Relationship between mirtazapine dose and incidence of adrenergic side effects: An exploratory analysis.
Michael D ShumanAthena ChukwuNathan Van VeldhuizenSteven A MillerPublished in: The mental health clinician (2019)
This study failed to support the hypothesis that mirtazapine is more activating at higher doses and appears to support the safety of increasing dose without increasing risk of noradrenergic side effects. Prospective studies will be necessary to confirm these findings.