Impact of RB1 gene screening from blood collected on a single day from 411 family members of 113 Retinoblastoma survivors in India.
Ayyasamy VanniarajanPuja MaitraKaruvel Kannan SaraswathiParag K ShahPublished in: Eye (London, England) (2024)
The detection of a germline mutation impacts the proband and family members due to its implications on change in prognosis, frequency of subsequent evaluations, screening for ocular and non-ocular cancers, and surveillance of family and future progeny.