Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment.
Rosario MegnaBruno AlfanoRoberta LanzilloTeresa CostabileMarco ComerciGiovanni VaccaAntonio CarotenutoMarcello MocciaGiuseppe ServilloAnna PrinsterVincenzo Brescia MorraMario QuarantelliPublished in: Journal of neurology (2018)
In RR-MS the tissue damage in white matter lesions appears the single main determinant of the cognitive status of patients, likely through disconnection phenomena, while the physical disability appears related to the involvement of gray matter.
Keyphrases
- multiple sclerosis
- white matter
- cognitive impairment
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- mass spectrometry
- oxidative stress
- physical activity
- mental health
- peritoneal dialysis
- prognostic factors
- resting state
- ms ms
- patient reported outcomes
- single molecule
- functional connectivity
- brain injury