Periostin and Epithelial-Mesenchymal Transition Score as Novel Prognostic Markers for Leiomyosarcoma, Myxofibrosarcoma, and Undifferentiated Pleomorphic Sarcoma.
Maria Assunta PianoAntonella BrunelloRocco CappellessoPaola Del BiancoAdriana MattioloChiara FritegottoBarbara MontiniCarolina ZamunerPaolo Del FioreMarco RastrelliAntonio SommarivaGian Luca De SalvoMaria Cristina MontescoCarlo Riccardo RossiVittorina ZagonelMaria Luisa CalabròPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Although limited to a pilot study, these findings suggest that periostin might contribute prognostic information in the three studied STS histotypes. Moreover, a transitioning EMT score measured in the tumor might predict a less active and a more chemosensitive disease.