Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II.
Maaike H M OonkBrian M SlomovitzPeter J W BaldwinHelena C van DoornJacobus van der VeldenJoanne A de HulluKatja N GaarenstroomBrigitte F M SlangenIgnace VergoteMats BrännströmEleonora B L van DorstWillemien J van DrielRalph H HermansDavid NunnsMartin WidschwendterDavid NugentCathrine M HollandAarti SharmaPaul A DiSilvestroRobert MannelDorry BollDavid CibulaAl CovensDiane ProvencherIngo B RunnebaumDavid LuesleyPatricia EllisTimothy J DuncanMing Y TjiongDerek J CruickshankPreben KjølhedeCharles F LevenbackJiri BoudaKatharina E KieserConnie PalleNicola M SpirtosDavid M O'MalleyMario L LeitaoMelissa A GellerKalyan DharViren AsherKarl TamussinoDaniel H TobiasChrister BorgfeldtJayanthi S LeaJo BaileyMargareta LoodBrynhildur EyjolfsdottirStephen Attard-MontaltoKrishnansu S TewariRanjit ManchandaPernille Tine JensenPar PerssonLinda Van LeHein PutterGeertruida H de BockBradley J MonkCarien L CreutzbergAte G J van der ZeePublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
Inguinofemoral radiotherapy is a safe alternative for IFL in patients with SN micrometastases, with minimal morbidity. For patients with SN macrometastasis, radiotherapy with a total dose of 50 Gy resulted in more isolated groin recurrences compared with IFL.